Apyrase ADP-High, Apyrase ADP-Premium , Reversible platelet stabilization
20/02/17
Agro-Bio launchs in primary hemostasis field with this first reagent: Apyrase ADP.
Research Use Only.
Agro-Bio’s Apyrase ADP is an enzyme extracted from a variety of Solanum tuberosum. After different processes, Agro-Bio provide two formulations of Apyrase :
- Apyrase ADP-High with an ADPase specific activity superior to 20 U/mg,
- Apyrase ADP-Premium with an ADPase specific activity superior to 200 U/mg.
This enzyme works on nucleotides by hydrolyzing their phosphate group. Thus addition of apyrase ADP in a platelet suspension degrades the nucleotides released during the platelet washing. In this way platelets cannot be activated by these nucleotides through their P2X1 and P2Y1 receptors and maintain their discoid shape. This procedure enables platelets to maintain in resting state from 5 to 8 hours. It increases the platelet stability time of 50% compared to PRP* – which is stable for 3 hours.
* Platelet-Rich Plasma
Product References
Apyrase ADP-High | Apyrase ADP-Premium | |||||||
|---|---|---|---|---|---|---|---|---|
Ref. | PY062310 | PY0623100 | PY0623200 | PY0623500 | PY062710 | PY0627100 | P0627200 | PY062500 |
Pack. | 10 U | 100 U | 200 U | 500 U | 10 U | 100 U | 200 U | 500 U |
These products are available freeze-dried in 100, 200 and 500 U packaging. Stored in their original state, they are stable for 2 years.
They also are available frozen in 1,000 and 2,000 U packaging – upon request. Contact us.